PROTEOBACTERIA >> Alpha >> Ehrlichia >> Ehrlichia canis

EHRLICHIA CANIS

Class: Alpha Proteobacteria
Genus: Ehrlichia
Species: Ehrlichia canis
Description: Ehrlichia canis is an obligate, intracellular bacterium that acts as the causative agent of Ehrlichiosis, a disease most commonly affecting canine species. This pathogen is present throughout the United States (but is most prominent in the South),South America, Asia, and Africa.Ehrlichia canis, a small obligately intracellular, tick-transmitted, gram-negative, alpha-proteobacterium, is the primary etiologic agent of globally distributed canine monocytic ehrlichiosis
Synonyms:
Source: This pathogen is present throughout the United States (but is most prominent in the South),South America, Asia, and Africa
Pathogenicity: causes canine monocytic ehrlichiosis, which is a tick-born disease that causes severe morbidity in domesticated and wild dogs. The brown dog tick, Rhipicephalus sanguineus, transfers the organism from its salivary glands to the animal when feeding. The bacterium infects monocytes and can spread throughout the lymphatic system including the spleen and liver, leading to hyperplasia (an abnormal increase in cell size and number).
Genbank: NC_007354.1   [Genome]    [Nucleotide]
Size (Mb): 1.32
GC %: 29
Genes: 972
CDS Number: 925
Reference: The genome of the obligately intracellular bacterium Ehrlichia canis reveals themes of complex membrane structure and immune evasion strategies. Mavromatis K, et al. J Bacteriol 2006 Jun. Bowman, Dwight; Little, Susan E.; Lorentzen, Leif; Shields, James; Sullivan, Michael P.; Carlin, Ellen P. (2009). "Prevalence and geographic distribution of Dirofilaria immitis, Borrelia burgdorferi, Ehrlichia canis, and Anaplasma phagocytophilum in dogs in the United States: Results of a national clinic-based serologic survey". Veterinary Parasitology. 160 (1–2): 138–48. doi:10.1016/j.vetpar.2008.10.093. PMID 19150176
Biochemical Tests: