PROTEOBACTERIA >> Beta >> Burkholderia >> Burkholderia mallei
BURKHOLDERIA MALLEI
| Class: | Beta Proteobacteria |
| Genus: | Burkholderia |
| Species: | Burkholderia mallei |
| Description: | Burkholderia mallei is a Gram-negative, bipolar, aerobic bacterium, a Burkholderia-genus human and animal pathogen causing glanders; the Latin name of this disease (malleus) gave its name to the species causing it. It is closely related to B. pseudomallei, and by multilocus sequence typing it is a subspecies of B. pseudomallei. B. mallei evolved from B. pseudomallei by selective reduction and deletions from the B. pseudomallei genome. Unlike closely related Burkholderia pseudomallei and other genus members, the bacterium is nonmotile; its shape is something between a rod and a coccus measuring some 1.5–3.0 μm in length and 0.5–1.0 μm in diameter with rounded ends. |
| Synonyms: | |
| Source: | Isolated from human & animal samples |
| Pathogenicity: | The caussative agent of glanders (farcy, morve, morva) in humans (pneumonia, bacteremia) and animals. Horses and donkeys are the most susceptible. Hamsters proved to be highly susceptible to B. mallei experimental infection.Can produce a polysaccharide capsule, protecting the cell from phagocytosis. |
| Genbank: | NC_006348.1 [Genome] [Nucleotide] |
| Size (Mb): | 3.51 |
| GC %: | 68.2 |
| Genes: | |
| CDS Number: | |
| Reference: | Pseudomonas pseudomallei i Pseudomonas mallei --kapsuloobrazuiushchie bakterii. S F Popov, V Ia Kurilov, and A T Iakovlev. Zh Mikrobiol Epidemiol Immunobiol. 1995 Sep–Oct; (5): 32–36. |
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