PROTEOBACTERIA >> Gamma >> Actinobacillus >> Actinobacillus pleuropneumoniae

ACTINOBACILLUS PLEUROPNEUMONIAE

Class: Gamma Proteobacteria
Genus: Actinobacillus
Species: Actinobacillus pleuropneumoniae
Description: Cell characteristics: gram-negative, nonmotile, nonsporeforming, small,coccoid to rod-shaped cells occurring singly, in pairs, or short chains; not acid-fast; cells contain demethyl-menaquinone and ubiquinone.Surface colonies: colonies on chocolate agar are smooth and greyish white and reach3 mm in diameter after 48 h in a candle jar at 37°C; colonies on sheep blood agar produce a narrow zone of complete hemolysis, which is enlarged by staphylococcal β-lysin. Mesophilic; chemoorganotrophic, with a pro- nounced growth response to fermentable carbohydrates in peptone media; the minimal nutritional requirements are not known. Atmospheric requirements: aerobic, microaerophilic in primary isolation, facultatively anaerobic; no additional carbon dioxide is required for growth in subcultures.
Synonyms:
Source: The biotype 2 strains described so far have been isolated from pneumonic lesions of swine; one strain was isolated from a cervical lymph node, and one was isolated from a joint.
Pathogenicity: biotype 2 strains have been repeatedly isolated as the etiological agent of enzootic porcine pleuropneumonia in Switzerland. Bacteremic generalizations and arthritis have occasionally been observed. Morbidity has been lower and the severity of clinical infections has been less in outbreaks caused by biotype 2 strains than in outbreaks caused by V factor-requiring strains.
Genbank: NC_009053.1   [Genome]    [Nucleotide]
Size (Mb): 2.27
GC %: 41.3
Genes: 2,166
CDS Number: 2,084
Reference: POHL (S.), BERTSCHINGER (H.U.), FREDERIKSEN (W.) and MANNHEIM (W.): Transfer of Haemophilus pleuropneumoniae and the Pasteurella haemolytica-like organism causing porcine necrotic pleuropneumonia to the genus Actinobacillus (Actinobacillus pleuropneumoniae comb. nov.) on the basis of phenotypic and deoxyribonucleic acid relatedness. Int. J. Syst. Bacteriol., 1983, 33, 510-514.
Biochemical Tests: