PROTEOBACTERIA >> Gamma >> Vibrio >> Vibrio cholerae

VIBRIO CHOLERAE

Class: Gamma Proteobacteria
Genus: Vibrio
Species: Vibrio cholerae
Description: Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype
Synonyms: Vibrio cholera (sic) Pacini 1854, "Kommabacillus" Koch 1884, "Bacillo virgola del Koch" Trevisan 1884, "Bacillus cholerae" (Pacini 1854) Trevisan 1884, "Bacillus cholerae-asiaticae" Trevisan 1884, "Pacinia cholerae-asiaticae" (Trevisan 1884) Trevisan 1885, "Spirillum cholerae-asiaticae" (Trevisan 1884) Zopf 1885, "Microspira comma" Schroeter 1886, "Spirillum cholerae" (Pacini 1854) Macé 1889, "Vibrio cholerae-asiaticae" (Trevisan 1884) Pfeiffer 1896, "Vibrio comma" (Schroeter 1886) Blanchard 1906, "Liquidivibrio cholerae" (Pacini 1854) Orla-Jensen 1909.
Source: Although it is a human patogen, these are part of the normal aquatic flora in estuarine and brackish waters.
Pathogenicity: Causative agent of cholera, an acute life-threatening diarrhoeal disease which occurs in many developing countries,particularly in South Asia,Africa and latin America.
Genbank: NC_002505.1   [Genome]    [Nucleotide]
Size (Mb): 2.96
GC %: 47.7
Genes:
CDS Number:
Reference: Vibrio Cholerae: Genomics and Molecular Biology edited by Shah M. Faruque, G. Balakrish Nair p.1
Biochemical Tests: